This little tutorial only applies to those of using the blogger comment system.
Step One: First, you should check to make sure that you are being notified when someone leaves a comment on your blog.
When someone comments on one of my posts, I get an email that usually looks like the one below (if you are a no-reply blogger). This makes me sad because I can't reply to you and unless you come back to the original post you won't know that I responded.
I have found this to be important because I had no idea if anyone was responding to me unless I went back to the original post and scrolled down to check (and who has time for that!?). Since I am now a "reply" blogger...when I comment on someone's blog, they get a notification in their email (see step one), and they can just hit "reply" in their email and write me back. Easy easy! I've had a difficult time figuring out if I should reply on comments, on email, or on both. I've decided to only reply via email unless someone asks something and I think the response would be helpful to anyone else reading.
I hope this was helpful!